Uncovering the Molecular Basis of Protein-Protein Interactions: Essential for Life
Scientists have discovered the molecular basis of how an essential protein in our cells interacts with its partner protein. This could help to improve the understanding of diseases such as cancer and Alzheimer’s, as well as lead to the development of new treatments. The research team, led by scientists from the University of Copenhagen, used advanced imaging techniques to study the interaction between the two proteins, called p53 and TP53BP1. The findings, published in the journal Cell Reports, show that the two proteins form a complex which is essential for the functioning of cells in the body. The researchers also found that the interaction between the two proteins can be disrupted when the proteins are mutated, leading to a range of diseases such as cancer and Alzheimer’s. This discovery provides valuable insights into the molecular basis of these diseases and may help researchers develop new treatments in the future.
source: Phys.org