Today, scientists have discovered a new method for downregulating a gene in the human body. This gene, known as PPM1D, has been linked to a variety of cancers and other diseases. In a recent study, researchers were able to successfully downregulate PPM1D using a technique called CRISPR-Cas9. This method uses a complex of proteins to target and modify specific DNA sequences in the genome. By modifying the DNA sequences, scientists are able to manipulate or “turn off” certain genes. In this case, researchers were able to downregulate PPM1D in human cells, which could potentially lead to new treatments for diseases associated with this gene.

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source: Phys.org