Unveiling a Key Enzyme in the Fight Against Heart Failure: The Promise of a New Drug
A research team at the University of Wisconsin-Madison has recently revealed a key enzyme in heart failure that could be targeted by drugs for potential treatments. The enzyme, called SIRT1, is known to control energy metabolism and is involved in the protection against oxidative stress, both of which are known to play a role in heart failure. The team was able to identify the enzyme by studying mice with heart disease, and then used the information to create a drug that could be used to target the enzyme. The drug, called SRT1720, was able to improve the mice’s heart function. This research opens up the possibility of new treatments for heart failure, which can be a serious and debilitating condition.
source: Phys.org