A Breakthrough in Understanding the Cause of Xeroderma Pigmentosum: The Discovery of the Causative Gene
Xeroderma Pigmentosum (XP) is a rare genetic skin disorder characterized by extreme sensitivity to sunlight and an increased risk of skin cancer. However, the exact cause of XP has remained elusive until now. In a major breakthrough, researchers have identified a gene responsible for the condition, opening the door to new treatments. The team from the University of Arizona found that mutations in the gene, XPC, are responsible for XP. This gene is part of a larger group that helps repair DNA damage caused by ultraviolet radiation from the sun. Mutations in this gene prevent the body from repairing this damage, leading to the symptoms of XP. The team’s findings could lead to the development of treatments that target the XPC gene, helping individuals with XP to safely venture outdoors.
source: Phys.org