A new imaging technique developed by researchers at the University of Cambridge could revolutionize tissue imaging. The technique, called Sparse Label Multiphoton Tomography (SLMT), is capable of capturing entire 3D tissues in high resolution. SLMT works by labeling select cells with fluorescent markers and then using two-photon microscopy to image the labeled cells. This allows researchers to produce detailed 3D images of the tissue without having to take thin slices of the tissue, which can damage the sample. SLMT is the first imaging technique to provide both high-resolution 3D imaging and single-cell labeling. The imaging technique could be used in a wide range of scientific research, from understanding the structure of developing embryos to exploring the effects of diseases on cells.

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source: Phys.org