Today, scientists have made an exciting discovery about mammalian mitochondrial function: it requires a high level of fidelity in order to properly function. This means that the mitochondrial genome, or mtDNA, must remain stable and intact in cells for the mitochondria to work efficiently. Scientists now believe that maintaining this level of mtDNA stability is essential for the proper functioning of many cellular processes, including energy production, maintenance of cellular structure and metabolism, and stress response. This discovery has important implications for the development of drugs and treatments to address mitochondrial dysfunction in a wide variety of diseases, including cancer, heart disease, and neurological disorders.

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source: Phys.org