A groundbreaking new study has revealed that ibogaine compounds may be effective in treating addiction and depression. Ibogaine is a naturally occurring psychoactive compound derived from the African shrub, Tabernanthe iboga. In recent years, ibogaine has been used off-label as a treatment for addiction, particularly opioid addiction, as well as for depression and anxiety. Now, a team of researchers from the University of California, San Francisco has found that ibogaine compounds may be effective in treating addiction and depression due to their ability to act on the brain’s reward system. The team found that ibogaine and its derivatives increased levels of the neurotransmitter dopamine, and reduced withdrawal symptoms in animal models of addiction. The results of this study suggest that ibogaine and its derivatives may be effective treatments for addiction and depression.

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source: Phys.org