Unveiling the Mysteries of Hydrophobicity and its Impact on Proteins
A new study from researchers at the University of Michigan has revealed an exciting development in protein engineering. For the first time, they were able to manipulate the hydrophobicity of a protein, allowing them to control how the protein interacts with its environment. This could have major implications for drug development, as drugs that are designed to interact with proteins and other molecules in a specific way could be more effectively targeted. The team used a technique called “protein engineering” to modify the hydrophobicity of a protein, which allowed them to change how the protein interacted with its environment. They tested their technique on a protein called NEMO and were able to change the hydrophobicity of the protein from hydrophilic to hydrophobic. This could have major implications for drug development, as it could allow for more targeted drugs that interact with proteins in specific ways.
source: Phys.org