A new study by scientists at the University of California, Irvine has provided proof that marker-free DNA editing is a safe and efficient way to modify the genome of living organisms. The study, which was published in Nature Communications, found that marker-free editing was able to achieve a high editing efficiency with minimal off-target effects. This breakthrough could have far-reaching implications for medical treatments and gene therapy.

The marker-free editing technique, which is based on a modified CRISPR-Cas9 system, is much more precise and efficient than traditional marker-based editing methods. In the study, the researchers were able to modify the genome of Arabidopsis thaliana, a common model organism, with a high success rate and minimal off-target effects. This demonstrates that marker-free editing can be used to make precise and safe modifications to the genome of living organisms.

The implications of this study are huge. Marker-free editing could be used to develop new treatments for genetic diseases, as well as gene therapies to cure diseases and even extend life. This breakthrough could lead to a whole new era of medical treatments and therapies.

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source: Phys.org